19 August 2022

Paper published in `iScience`

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Our first collaborative paper with the Dr. Alla V Tsytsykova and colleagues in the Lab of the Ian Dunn in the Department of Neurosurgery, OUHSC, was published on-line in the journal iScience: Mutated KLF4(K409Q) in meningioma binds STRs and activates FGF3 gene expression . Francis made and purified four recombinant versions of KLF4. This work was done towards understanding how the K409Q mutant triggers the development of brain tumors. This work was funded by a Team Science grant from the Presbyterian Health Foundation.

tags: Francis Acquah - brain cancer - protein purification